The traditional Chinese medicine crusher has four major problems that require strict process requirements.

The appearance of Chinese medicine grinder is a major breakthrough in the development of the pharmaceutical industry. It not only makes the pharmaceutical production efficiency greatly improved, but also makes the dose more accurate, the efficacy is better, and the patient can get better protection. With the rapid development of China's pharmaceutical industry, traditional Chinese medicine crushers are widely used. Not only are they welcomed by numerous pharmaceutical factories and many large, medium and small pharmacies, but also many families have begun to use such pharmaceutical machines. Sales volume has increased year by year. Why are Chinese medicine grinders so popular? The industry stated that this is determined by its own superiority.
For example, the Chinese medicine crusher is mainly composed of steel, and part of it is produced by welding. There are strict requirements for the selection of gas welding wire. the first. It is necessary to consider the mechanical properties of the base metal of the traditional Chinese medicine crusher. Secondly, we must also consider the stress of the welding part of the traditional Chinese medicine crusher. For weldments with high requirements for the strength of welded joints, weld wires of higher strength than the parent metal must be selected. According to the industry, one of the principles of selecting wire materials for the Chinese medicine crusher is to meet the performance requirements of the weldment. Third, consider the weldability of traditional Chinese medicine grinders. In addition to considering the strength of the welding wire, the fusion of the weld metal and the parent metal and the uniformity of the organization must be considered. Generally, the melting point of the welding wire should be equal to or slightly lower than the melting point of the parent metal. Otherwise, defects such as burn-through, undercut and slag inclusion are easily formed during gas welding.

In the production of a shredder workshop for Chinese medicine, the welding groove of the beam web and wing T-joint in the company's workshop is machined using a planer machine. Prior to assembly and positioning, oxides and rust within 50 mm of the groove face and both sides of the web were removed with a high-speed grinder, and oxide rust within a range of 100 mm at the center of the wing width direction was thoroughly cleaned.

Lay down on a dedicated bench and form an I-beam. The I-beams are always spot welded. The spot welding length is 100-200mm, the spacing is not more than 400mm, and the thickness is equal to half of the groove depth.

According to the material and structure requirements of the workshop beam, 1.2mmH08Mn2Si copper-plated welding wire is used for gas shielded welding. The quality of the welding wire must meet the requirements of the international GB-1700 standard. To prevent weld cracks caused by large structural welding stress, the carbon content of the welding wire should be controlled. 0.08% or less. In addition, CO 2 +Ar mixed gas should be used when welding the steel structure workshop of the Chinese medicine grinder. The mixing ratio is 1:1. The water content of bottled CO2 must be strictly controlled below 0.5%. Before use, the bottle should be inverted for more than 8 hours to remove water. When the bottle internal pressure is lower than 1MP, it should be stopped to prevent the generation of pores in the weld and reduce the hydrogen content in the weld. the amount. The CO2 gas shielded welding is used as the base, and the automatic submerged arc welding machine is followed by the capping layer welding. The welding speeds for the bottom layer and cover are generally about 24 to 28 meters per hour.

The workshop of Chinese medicine grinder is very strict with regard to the welding process, and it is precisely because of the high requirements of traditional Chinese medicine grinders for various processes. The appearance of traditional Chinese medicine grinders has greatly improved the technical level of the pharmaceutical industry. Traditional Chinese medicine grinders are used as advanced Chinese medicine processing equipment. Its unique fineness advantage will certainly inject new vitality into the development of Chinese medicine and meet the needs of the country in vigorously developing the Chinese medicine industry.

However, compared with the advanced level in foreign countries, although China's traditional Chinese medicine crusher currently has a certain degree of technical improvement, the bottleneck of research and development has not yet been able to break through. China's traditional Chinese medicine crusher still has much to be learned and innovated in terms of technology and quality. However, at present, there are several problems that need to be solved in the traditional Chinese medicine pulverizer. After summarizing the new source pharmacy machines, they are summarized as follows:

The problem of powder aggregation: The specific surface area of ​​the drug after supermicronization increases significantly, the surface energy is high, and there is a strong tendency to attract each other to achieve stability. In order to prevent the aggregation of the powder and make it in a monodispersed state, appropriate surface treatment and packaging techniques may be adopted.

The technical problems in the process of chemical extraction: The application of Chinese medicine is nothing more than two ways: extraction and direct drug use. From the perspective of extraction, there are two problems, one is the dispersion of powders, and the other is the gelatinization in the extraction process. This requires the selection and optimization of extraction process parameters (including extraction temperature, extraction time, and solvent extraction Kinds, etc.) to solve.

Technical problems in the in vitro dissolution assay: From the perspective of the direct use of traditional Chinese medicines, the core problem of preparations made with ultra-fine Chinese medicine powders is the establishment of in vitro dissolution techniques. The solution to this problem was to conduct a methodological investigation of screening dissolution media and dissolution methods, and comprehensive selection of indicator components.

Pharmacodynamically proven technical problems: Pharmacodynamics is the most powerful means of verifying whether the effective ingredients are preserved and enhanced after the Chinese medicine is crushed. After the Chinese medicine is crushed, it can significantly improve the pharmacodynamic activity of the medicinal materials, and remains to be verified.

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